발생유전학 연구실 (Developmental Genetics Laboratory)
이승복 교수|Seung-bok Lee,
Ph.D.
학력
- 서울대학교 자연대학 미생물학과 이학사 (1986)
- 서울대학교 자연대학 미생물학과 이학석사 (1988)
- Univ. of Wisconsin-Madison, USA 이학박사 (1997)
연구분야
- Molecular mechanisms of axon guidance, synaptogenesis and synaptic plasticity.
- Molecular genetics of olfactory learning and memory.
- Regulation of fat metabolism by neuropeptides and GPCRs.
주요 연구방법
- Molecular cloning & Cell biology (exocytosis/endocytosis, lipid assay, cell signaling).
- Immunochemistry & Electron microscopy.
- Fly & mouse genetics.
대표 연구업적
- Nahm M, Lee MJ, Parkinson W, Lee M, Kim YJ, Kim S, Min BM, Broadie K, Lee S (2012) Spartin regulates synaptic growth and neuronal survival by inhibiting BMP-mediated microtubule stabilization. (Submitted ).
- Nahm M, Long AA, Paik SK, Kim S, Bae YC, Broadie K, Lee S (2010) The Cdc42-selective GAP Rich regulates postsynaptic development and retrograde BMP transsynaptic signaling. J. Cell Biol. 191(3):661-675.
- Nahm M, Kim S, Paik SK, Lee M, Lee S, Lee ZH, Kim J, Lee D, Bae YC, Lee S (2010) dCIP4 (Drosophila Cdc42-Interacting Protein 4) Restrains Synaptic Growth by Inhibiting the Secretion of the Retrograde Glass Bottom Boat Signal. J. Neurosci. 30(24):8138-8150.
- Lee M, Paik SK, Lee MJ, Oh S, Kim YJ, Kim S, Nahm M, Kim HM, Yim J, Lee CJ, Bae YC, Lee S (2009) Drosophila Atlastin regulates the stability of muscle microtubules and is required for synapse development. Dev. Biol. 330:250-262.
- Lee S, Nahm M, Lee M, Kwon M, Kim E, Zadeh AD, Cao H, Kim HJ, Lee ZH, Oh SB, Yim J, Kolodziej PA, Lee S (2007) The Factin- microtubule crosslinker Shot is a platform for Krasavietzmediated translational regulation of midline axon repulsion. Development. 134(9):1767-1777.
Tel: 02-740-8737 Fax: 02-762-2583 E-mail: seunglee@snu.ac.kr